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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10316038 B1

PDFFull Text
Date of Patent:
Jun. 11, 2019

Filed:

Jan. 25, 2018

Pyrrolopyrimidine itk inhibitors for treating inflammation and cancer

Applicant:

Aclaris Therapeutics, Inc., Wayne, PA (US);

Inventors:

Eric Jon Jacobsen, Chesterfield, MO (US);

James Robert Blinn, O'Fallon, MO (US);

John Robert Springer, Wentzville, MO (US);

Susan Landis Hockerman, Kirkwood, MO (US);

David Randolph Anderson, Salem, CT (US);

Assignee:

ACLARIS THERAPEUTICS, INC., Wayne, PA (US);

Attorney:

Pepper Hamilton LLP

Primary Examiner:

Niloofar Rahmani

Int. Cl.
CPC ...
C07D 401/10 (2006.01); C07D 401/14 (2006.01); A61K 31/437 (2006.01); A61K 31/4353 (2006.01); C07D 471/04 (2006.01); A61P 29/00 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61P 29/00 (2018.01); C07D 519/00 (2013.01);
Abstract

Disclosed herein are arylpyridinone compounds and compositions useful in the treatment of ITK mediated diseases, such as inflammation, having the structure of Formula (I): wherein R, R, and X are as defined in the detailed description. Methods of inhibition of ITK activity in a human or animal subject are also provided.

Find Patent Forward Citations

Jacobsen, Eric. (2019). Pyrrolopyrimidine itk inhibitors for treating inflammation and cancer (U.S. Patent No. 10316038). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10316038

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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