The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 11, 2019
Filed:
Nov. 04, 2016
Applicant:
Daiichi Sankyo Company, Limited, Tokyo, JP;
Inventors:
Kohei Kadota, Tokyo, JP;
Tsuyoshi Ueda, Tokyo, JP;
Assignee:
DAIICHI SANKYO COMPANY, LIMITED, Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 213/76 (2006.01); C07D 239/69 (2006.01); C07D 277/52 (2006.01); C07D 403/12 (2006.01);
U.S. Cl.
CPC ...
C07D 403/12 (2013.01); C07D 213/76 (2013.01); C07D 239/69 (2013.01); C07D 277/52 (2013.01);
Abstract
In a method for producing a de-dimethoxybenzylated compound by removing a dimethoxybenzyl group from a compound containing a dimethoxybenzyl group bonded to a nitrogen atom in the presence of an acid, the de-dimethoxybenzylated compound is obtained by removing the dimethoxybenzyl group without forming a poorly soluble product resulting from the removed dimethoxybenzyl group. The de-dimethoxybenzylation reaction is carried out in the presence of triphenylphosphine or diethylthiourea.