The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 11, 2019

Filed:

Nov. 22, 2017
Applicant:

Pfizer Inc., New York, NY (US);

Inventors:

Natasha Mariam Kablaoui, Newton, MA (US);

Michael Eric Green, Boston, MA (US);

Justin Ian Montgomery, Ledyard, CT (US);

Michael Aaron Brodney, Newton, MA (US);

Patrick Robert Verhoest, Newton, MA (US);

Gregory Wayne Kauffman, East Greenwich, RI (US);

Danica Antonia Rankic, New London, CT (US);

Scot Richard Mente, Arlington, MA (US);

Bruce Nelsen Rogers, Belmont, MA (US);

Kapildev Kashmirilal Arora, Niantic, CT (US);

Matthew Francis Dunn, Middletown, CT (US);

Assignee:

Pfizer Inc., New York, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/04 (2006.01); C07D 231/20 (2006.01); C07D 413/04 (2006.01); C07D 417/04 (2006.01); A61P 25/00 (2006.01);
U.S. Cl.
CPC ...
C07D 403/04 (2013.01); A61P 25/00 (2018.01); C07D 231/20 (2013.01); C07D 413/04 (2013.01); C07D 417/04 (2013.01); C07B 2200/13 (2013.01);
Abstract

The present invention provides compounds of Formula I: and pharmaceutically acceptable salts thereof wherein the variables R, R, R, R, R, X, m and n are as defined herein; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds or salts, and their uses for treating kappa opioid (κ-opioid) associated disorders including, e.g., a neurological disorder, or psychiatric disorder such as a neurocognitive disorder, substance abuse disorder, depressive disorder, anxiety disorder, trauma and stressor related disorder and feeding and eating disorder.


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