The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 11, 2019

Filed:

Dec. 28, 2018
Applicant:

Oriental (Luzhou) Agrochemicals. Co., Ltd., Luzhou, Sichuan, CN;

Inventors:

Qiuju Sheng, Zhejiang, CN;

Zhiming Zhang, Zhejiang, CN;

Junliang Wang, Zhejiang, CN;

Bangchi Chen, Zhejiang, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 249/12 (2006.01); C07C 251/78 (2006.01);
U.S. Cl.
CPC ...
C07D 249/12 (2013.01); C07C 251/78 (2013.01); C07B 2200/07 (2013.01);
Abstract

Disclosed are a method of synthesizing prothioconazole and optically active isomers thereof and intermediates. The method includes reacting hydrazine with glyoxylic acid to produce a hydrazono acetic acid as an intermediate, and then reacting the intermediate with thiocyanate to produce the target product prothioconazole. The present method is very specific in terms of regioselectivity, resulting in minimum byproducts and a high product yield. The present method does not require special equipment, nor anhydrous or oxygen-free manipulations. The process is simple and generates minimum wastes, suitable for industrial production.


Find Patent Forward Citations

Loading…