The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 11, 2019
Filed:
Jun. 03, 2016
Lead Pharma Holding B.v., Nijmegen, NL;
Sanofi, Paris, FR;
Joseph Maria Gerardus Barbara Cals, Oss, NL;
Vera De Kimpe, Oss, NL;
Sander Bernardus Nabuurs, Oss, NL;
LEAD PHARMA HOLDING B.V., Nijmegen, NL;
SANOFI, Paris, FR;
Abstract
Compounds according to Formula I: or a pharmaceutically acceptable salt wherein: Ais NRor CR, with Rherein; the cyclopropyl moiety with one or more methyl and one or more F; A-Aare N or CR-CR, with no more than two of the four positions A in A-Acan be simultaneously N; R-Rare described; Rand Rare independently H, F, methyl, ethyl, hydroxyl or methoxy or Rand Rtogether is carbonyl, all alkyl groups, if substituted with one or more F; Ris H or C(1-6)alkyl; A-Aare N or CR-CR, with no more than two of the four positions A in A-Acan be simultaneously N; R-Rherein; Rand Rherein; or Rand Rfused forming a ring having 5 to 7 atoms by joining Rbeing C(1-6)alkyl or C(2-6)alkenyl. The RORγ compounds can treat RORγ mediated diseases.