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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10315993 B1

PDFFull Text
Date of Patent:
Jun. 11, 2019

Filed:

Apr. 25, 2018

Synergistic compositions

Applicant:

Cadila Healthcare Limited, Ahmedabad, Gujarat, IN;

Inventors:

Mukul R. Jain, Gujarat, IN;

Suresh Giri, Gujarat, IN;

Himanshu M. Kothari, Gujarat, IN;

Kaushik Banerjee, Gujarat, IN;

Rashmikant Kachhiya, Gujarat, IN;

Assignee:

Cadila Healthcare Limited, Ahmedabad, Gujarat, IN;

Attorney:

Goodwin Procter LLP

Primary Examiner:

Kristin A Vajda

Int. Cl.
CPC ...
C07D 207/333 (2006.01); C07C 215/40 (2006.01); A61K 38/26 (2006.01); C07D 295/027 (2006.01); A61K 31/4985 (2006.01); C07C 215/10 (2006.01); C07C 217/60 (2006.01); C07C 211/51 (2006.01); C07D 233/58 (2006.01); A61K 31/4015 (2006.01); C07C 211/11 (2006.01); C07C 215/12 (2006.01); C07C 211/30 (2006.01); C07C 229/26 (2006.01); A61K 31/40 (2006.01); A61K 31/155 (2006.01); C07C 211/27 (2006.01); A61K 31/64 (2006.01); A61K 31/505 (2006.01); C07C 211/35 (2006.01); A61K 45/06 (2006.01); C07C 279/14 (2006.01);
U.S. Cl.
CPC ...
C07D 207/333 (2013.01); A61K 31/155 (2013.01); A61K 31/40 (2013.01); A61K 31/4015 (2013.01); A61K 31/4985 (2013.01); A61K 31/505 (2013.01); A61K 31/64 (2013.01); A61K 38/26 (2013.01); A61K 45/06 (2013.01); C07C 211/11 (2013.01); C07C 211/27 (2013.01); C07C 211/30 (2013.01); C07C 211/35 (2013.01); C07C 211/51 (2013.01); C07C 215/10 (2013.01); C07C 215/12 (2013.01); C07C 215/40 (2013.01); C07C 217/60 (2013.01); C07C 229/26 (2013.01); C07C 279/14 (2013.01); C07D 233/58 (2013.01); C07D 295/027 (2013.01); A61K 2300/00 (2013.01); C07C 2601/14 (2017.05);
Abstract

The present invention describes a synergistic composition comprising of one or more statins, or one or more dipeptidyl peptidase IV (DPP IV) inhibitor or one or more biguanide antihyperglycaemic agent and a PPAR agonist of formula (Ia) for the treatment of diabetes, especially non-insulin dependent diabetes (NIDDM) or Type 2 diabetes and conditions associated with diabetes mellitus and to compositions suitable for use in such method. The invention also describes the preparation of such compositions. The present invention also relates to certain novel salts of the PPAR agonist of formula (I), processes for the preparation of these novel salts and use thereof.

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