The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 11, 2019
Filed:
Sep. 17, 2014
Apparatus and process for the preparation of a biomimetic tissue prosthesis of the tympanic membrane
Applicant:
Azienda Ospedaliero-universitaria Pisana, Pisa, IT;
Inventors:
Serena Danti, Pistoia, IT;
Stefano Berrettini, Lucca, IT;
Stefano Marrazza, Pistoia, IT;
Cesare Stefanini, Vicopisano, IT;
Assignee:
Azienda Ospedaliero-Universitaria Pisana, Pisa, IT;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12M 1/42 (2006.01); C12M 3/00 (2006.01); C12N 5/0775 (2010.01); A61L 27/36 (2006.01); A61L 27/58 (2006.01); A61F 2/18 (2006.01);
U.S. Cl.
CPC ...
A61L 27/3645 (2013.01); A61L 27/3604 (2013.01); A61L 27/58 (2013.01); C12M 21/08 (2013.01); C12M 35/06 (2013.01); C12N 5/0663 (2013.01); A61F 2002/183 (2013.01); A61F 2240/001 (2013.01); A61L 2430/14 (2013.01); C12N 2500/38 (2013.01); C12N 2501/15 (2013.01); C12N 2521/00 (2013.01); C12N 2533/18 (2013.01); C12N 2533/30 (2013.01);
Abstract
The present invention refers to a process, and to the related apparatus, for the in vitro preparation of a biomimetic tissue prostheses of the tympanic membrane from mesenchymal stem cells; such prostheses are used for repairing or reconstructing the injured tympanic membrane in patients needing it, for example as a consequence of various trauma or pathologies.