The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 11, 2019

Filed:

Jan. 25, 2018
Applicants:

Institut Pasteur, Paris, FR;

Centre National DE LA Recherche Scientifique, Paris, FR;

Institut National DE LA Sante ET DE LA Recherche Medicale, Paris, FR;

Universite DE Nantes, Nantes, FR;

Inventors:

Frédéric Tangy, Les Lilas, FR;

Marc Gregoire, Nantes, FR;

Jean-François Fonteneau, Nantes, FR;

Jean-Baptiste Guillerme, Nantes, FR;

Chantal Combredet, Paris, FR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/165 (2006.01); A61K 35/768 (2015.01); C12N 7/00 (2006.01); A61K 35/15 (2015.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/165 (2013.01); A61K 35/15 (2013.01); A61K 35/768 (2013.01); C12N 7/00 (2013.01); A61K 2039/5154 (2013.01); A61K 2039/5254 (2013.01); C12N 2760/18421 (2013.01); C12N 2760/18432 (2013.01); C12N 2760/18434 (2013.01); C12N 2760/18462 (2013.01);
Abstract

The invention relates to a genetically modified infectious measles virus derived from a live-attenuated measles virus strain, in which the gene encoding the viral accessory C protein has been knocked out (MV-deltaC). It concerns in particular the use of said genetically modified infectious MV-deltaC in the treatment of malignant tumor or cancer conditions, and for the preparation of agents or compositions for such treatment.


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