The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 11, 2019
Filed:
Mar. 19, 2014
Applicants:
Sunnybrook Research Institute, Toronto, CA;
Unity Health Toronto, Toronto, CA;
Inventors:
Assignees:
Sunnybrook Research Institute, Toronto, ON, unknown;
Unity Health Toronto, Toronto, ON, unknown;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/08 (2019.01); A61K 38/10 (2006.01); A61K 38/16 (2006.01); A61K 38/18 (2006.01); A61P 31/12 (2006.01); A61P 31/16 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01); C07K 14/515 (2006.01); C07K 14/475 (2006.01); A61K 31/13 (2006.01); A61K 31/195 (2006.01); A61K 31/7056 (2006.01); A61K 31/215 (2006.01); A61K 31/7012 (2006.01); A61K 45/06 (2006.01); A61K 47/60 (2017.01); C07K 14/705 (2006.01); C07K 14/71 (2006.01); A61K 38/17 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/08 (2013.01); A61K 31/13 (2013.01); A61K 31/195 (2013.01); A61K 31/215 (2013.01); A61K 31/7012 (2013.01); A61K 31/7056 (2013.01); A61K 38/10 (2013.01); A61K 38/1891 (2013.01); A61K 45/06 (2013.01); A61K 47/60 (2017.08); A61P 31/12 (2018.01); A61P 31/16 (2018.01); C07K 7/06 (2013.01); C07K 7/08 (2013.01); C07K 14/515 (2013.01); A61K 38/00 (2013.01); A61K 38/16 (2013.01); A61K 38/179 (2013.01); A61K 38/18 (2013.01); C07K 14/475 (2013.01); C07K 14/705 (2013.01); C07K 14/71 (2013.01);
Abstract
The present disclosure provides methods and uses of Tie2 agonists alone or in combination with antiviral agents. In particular, the present disclosure provides methods and uses for treating influenza, treating a bacterial superinfection associated with influenza and decreasing lung endothelial leakage. The disclosure also provides compositions comprising (a) a Tie2 agonist and (b) an antiviral agent and methods and uses thereof.