The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 11, 2019

Filed:

May. 16, 2016
Applicant:

University of Iowa Research Foundation, Iowa City, IA (US);

Inventors:

Aliasger K. Salem, Coralville, IA (US);

Amani Makkouk, Iowa City, IA (US);

Vijaya B. Joshi, Minneapolis, MN (US);

George Weiner, Iowa City, IA (US);

Assignee:

University of Iowa Foundation, Iowa City, IA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/704 (2006.01); A61K 9/00 (2006.01); A61K 47/34 (2017.01); C07K 16/28 (2006.01); A61P 35/00 (2006.01); A61K 9/16 (2006.01); A61K 31/7088 (2006.01); A61K 39/39 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/704 (2013.01); A61K 9/0019 (2013.01); A61K 9/1647 (2013.01); A61K 31/7088 (2013.01); A61K 47/34 (2013.01); A61P 35/00 (2018.01); C07K 16/2818 (2013.01); C07K 16/2878 (2013.01); A61K 39/0011 (2013.01); A61K 39/39 (2013.01); A61K 2039/505 (2013.01); A61K 2039/507 (2013.01); A61K 2039/54 (2013.01); A61K 2039/55561 (2013.01); A61K 2039/585 (2013.01); C07K 2317/75 (2013.01);
Abstract

Disclosed are compositions, kits, and methods for treating cancer in a subject in need thereof. The compositions, kits, and methods may be used to treat a tumor in a subject in situ. The compositions, kits, and methods comprise or utilize cytotoxic particles, immune checkpoint inhibitors, and/or T-cell stimulatory agents.


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