The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 11, 2019
Filed:
Aug. 18, 2016
Applicant:
The Methodist Hospital, Houston, TX (US);
Inventors:
Assignee:
The Methodist Hospital, Houston, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61P 1/12 (2006.01); A61K 31/12 (2006.01); A61K 45/06 (2006.01); A61K 31/121 (2006.01); A61K 31/352 (2006.01); A61K 31/353 (2006.01); A61K 31/4745 (2006.01);
U.S. Cl.
CPC ...
A61K 31/352 (2013.01); A61K 9/0053 (2013.01); A61K 31/12 (2013.01); A61K 31/121 (2013.01); A61K 31/353 (2013.01); A61K 31/4745 (2013.01); A61K 45/06 (2013.01); A61P 1/12 (2018.01);
Abstract
A method for treating diarrhea induced by a chemotherapy agent by administering a carboxylesterase 2 (CES2) inhibitor, i.e., hesperetin, naringenin, or 2',4′-dihydroxychalcone. Also disclosed is a method for treating cancer by administering a chemotherapy agent together with hesperetin, naringenin, or 2′,4′-dihydroxychalcone. Furthermore, a composition for treating cancer is provided, the composition containing a chemotherapy agent and hesperetin, naringenin, or 2′,4′-dihydroxychalcone.