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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10312063 B1

PDFFull Text
Date of Patent:
Jun. 04, 2019

Filed:

Mar. 12, 2014

Eluate analysis and collection

Applicant:

Malvern Panalytical Limited, Worcestershire, GB;

Inventors:

Oksana Iryna Leszczyszyn, Worcestershire, GB;

Paul G. Clarke, Worcestershire, GB;

Mark Nicholls, Worcestershire, GB;

E. Neil Lewis, Worcestershire, GB;

Assignee:

Malvern Panalytical Limited, Malvern, Worcestershire, GB;

Attorney:

Morrison & Foerster LLP

Primary Examiner:

Maureen Wallenhorst

Int. Cl.
CPC ...
G01N 30/00 (2006.01); G01N 30/74 (2006.01); G01N 30/82 (2006.01); B01D 15/10 (2006.01); C07K 1/16 (2006.01); G01N 15/14 (2006.01); H01J 37/32 (2006.01); G01N 27/447 (2006.01); F16B 7/04 (2006.01); G01N 27/453 (2006.01); G01N 21/53 (2006.01); G01N 33/68 (2006.01); B01D 15/24 (2006.01); G01N 30/02 (2006.01);
U.S. Cl.
CPC ...
H01J 37/32807 (2013.01); B01D 15/10 (2013.01); C07K 1/16 (2013.01); F16B 7/0406 (2013.01); G01N 15/1404 (2013.01); G01N 27/44739 (2013.01); G01N 27/453 (2013.01); G01N 30/0005 (2013.01); G01N 30/74 (2013.01); G01N 30/82 (2013.01); H01J 37/32357 (2013.01); B01D 15/247 (2013.01); G01N 21/532 (2013.01); G01N 27/44721 (2013.01); G01N 33/68 (2013.01); G01N 2030/027 (2013.01); H01J 2237/334 (2013.01); Y10T 403/66 (2015.01);
Abstract

The invention relates to analyzing and controlling collection of liquid eluate output from a separation process, in particular by use of a measure of suspended material in the eluate based on a light scattering detection method. Exemplary embodiments include a method of controlling collection of a sample of a liquid eluate output from a separation process. The method includes exposing the liquid eluate to light from a light source; detecting light from the light source scattered by suspended material in the eluate at a detector; and beginning and ending collection of the sample when a measure of the suspended material derived from the detected scattered light enters and leaves a predetermined range.

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