The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 04, 2019

Filed:

Jun. 12, 2018
Applicant:

Bostongene Corporation, Lincoln, MA (US);

Inventors:

Alexander Bagaev, Moscow, RU;

Feliks Frenkel, Moscow, RU;

Nikita Kotlov, Moscow, RU;

Ravshan Ataullakhanov, Moscow, RU;

Assignee:

BostonGene Corporation, Lincoln, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G16B 5/00 (2019.01); G06F 16/28 (2019.01); G06F 17/18 (2006.01); G16B 20/00 (2019.01); G16B 40/00 (2019.01); G16B 45/00 (2019.01); G16B 50/00 (2019.01); G16H 10/20 (2018.01); G16H 20/00 (2018.01); G16H 20/10 (2018.01); G16H 20/40 (2018.01); G16H 50/20 (2018.01); G16H 50/30 (2018.01); G16H 50/50 (2018.01); G16H 50/70 (2018.01); G16H 70/20 (2018.01); C12Q 1/6886 (2018.01);
U.S. Cl.
CPC ...
G16B 45/00 (2019.02); C12Q 1/6886 (2013.01); G06F 16/285 (2019.01); G06F 17/18 (2013.01); G16B 5/00 (2019.02); G16B 20/00 (2019.02); G16B 40/00 (2019.02); G16B 50/00 (2019.02); G16H 10/20 (2018.01); G16H 20/00 (2018.01); G16H 20/10 (2018.01); G16H 20/40 (2018.01); G16H 50/20 (2018.01); G16H 50/30 (2018.01); G16H 50/50 (2018.01); G16H 50/70 (2018.01); G16H 70/20 (2018.01); C12Q 2600/156 (2013.01); C12Q 2600/158 (2013.01);
Abstract

Various methods, systems, computer readable media, and graphical user interfaces (GUIs) are presented and described that enable a subject, doctor, or user to characterize or classify various types of cancer precisely. Additionally, described herein are methods, systems, computer readable media, and GUIs that enable more effective specification of treatment and improved outcomes for patients with identified types of cancer. Some embodiments of the methods, systems, computer readable media, and GUIs described herein comprise obtaining RNA expression data and/or whole exome sequencing (WES) data for biological samples; determining a respective plurality of molecular-functional (MF) profiles for a plurality of subjects; clustering the plurality of MF profiles to obtain MF profile clusters; determining a molecular-functional (MF) profile for an additional subject; and identifying, from among the MF profile clusters, a particular MF profile cluster with which to associate the MF profile for the subject.


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