The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 04, 2019

Filed:

Nov. 03, 2016
Applicant:

The General Hospital Corporation, Boston, MA (US);

Inventors:

Bastien Guerin, Cambridge, MA (US);

Lawrence L Wald, Cambridge, MA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01R 33/28 (2006.01); G01R 33/561 (2006.01); G01R 33/56 (2006.01);
U.S. Cl.
CPC ...
G01R 33/288 (2013.01); G01R 33/5612 (2013.01); G01R 33/5605 (2013.01);
Abstract

Described here are a system and method for designing radio frequency ('RF') pulses for parallel transmission ('pTx') applications, and particularly pTx applications in magnetization transfer (“MT”) magnetic resonance imaging (“MRI”). The concept of “SAR hopping” is implemented using a constrained optimization problem that simultaneously designs multiple RF sub-pulses to maximize power deposition in a bound proton pool while also minimizing local SAR across multiple bound proton pool excitation frequencies. This results in the set of RF waveforms that yield the best excitation profiles for all pulses while ensuring that the local SAR of the average of all pulses is below the regulatory limit imposed by the FDA. Pulses are designed simultaneously while constraining local SAR, global SAR, and peak voltage, explicitly.


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