The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 04, 2019
Filed:
Mar. 13, 2014
Children's Medical Center Corporation, Boston, MA (US);
The Brigham and Women's Hospital, Inc., Boston, MA (US);
Dana-farber Cancer Institute, Inc., Boston, MA (US);
The Technical University of Denmark, Lyngby, DK;
Zoltan I. Szallasi, Boston, MA (US);
Andrea L. Richardson, Chestnut Hill, MA (US);
Nicolai J. Birkbak, København Ø, DK;
Zhigang Wang, Newton, MA (US);
CHILDREN'S MEDICAL CENTER CORPORATION, Boston, MA (US);
THE BRIGHAM AND WOMEN'S HOSPITAL, INC., Boston, MA (US);
DANA-FARBER CANCER INSTITUTE, INC., Boston, MA (US);
THE TECHNICAL UNIVERSITY OF DENMARK, KGS, Lyngby, DK;
Abstract
The present invention provides assays, methods and systems for selecting an effective therapy for a subset of cancer patients having cancer cells with increased expression of BML and FANCI genes and/or having copy number increase in chromosome location 15q26 in the cancer cells and for treatment of such patients with the effective therapy of cancer patients based on the personalized cancer cell expression profile.