The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 04, 2019
Filed:
Mar. 14, 2013
Agilent Technologies, Inc., Loveland, CO (US);
Brian Jon Peter, Loveland, CO (US);
Robert A. Ach, Loveland, CO (US);
Zoltan Timar, Loveland, CO (US);
Joel Myerson, Loveland, CO (US);
Jeffrey Robert Sampson, Loveland, CO (US);
Holly Hogrefe, Loveland, CO (US);
AGILENT TECHNOLOGIES, INC., Santa Clara, CA (US);
Abstract
This disclosure provides a method comprising: a) clamping the top and bottom strands of a double stranded DNA molecule to produce a duplex in which the top and bottom strands are linked; b) denaturing the duplex to produce a denatured product; and c) renaturing the denatured product in the presence of a labeled oligonucleotide that is complementary to a sequence of nucleotides in the double stranded DNA molecule, thereby producing a D-loop-containing product. Kits for performing the method and products made by the method are also provided.