The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 04, 2019

Filed:

Dec. 14, 2016
Applicant:

Korea Institute of Science and Technology, Seoul, KR;

Inventors:

Hak Suk Chung, Seoul, KR;

Eun Gyeong Yang, Seoul, KR;

Dohyeon Hwang, Seoul, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 19/12 (2006.01); C12N 15/70 (2006.01); C12N 9/10 (2006.01); C12N 9/16 (2006.01); C12N 15/52 (2006.01); C12N 15/74 (2006.01);
U.S. Cl.
CPC ...
C12N 15/70 (2013.01); C12N 9/1029 (2013.01); C12N 9/16 (2013.01); C12N 15/52 (2013.01); C12N 15/74 (2013.01); C12P 19/12 (2013.01);
Abstract

A bacterium producing monophosphoryl lipid A (MLA) comprising a genetic modification that increases expression of a gene encoding LpxE polypeptide and a method of producing MLA are provided. According to the present invention, MLA may be produced in a simple manner without acid hydrolysis and/or base hydrolysis.


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