The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 04, 2019
Filed:
May. 25, 2018
Applicant:
Vitrisa Therapeutics, Inc., Larkspur, CA (US);
Inventors:
Carl Erickson, Corte Madera, CA (US);
Christopher P. Rusconi, Durham, NC (US);
Kevin G. McLure, Oakland, CA (US);
Renta Hutabarat, Dracut, MA (US);
Assignee:
Vitrisa Therapeutics, Inc., Larkspur, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 45/06 (2006.01); C12N 15/113 (2010.01); C12N 15/115 (2010.01); A61K 9/00 (2006.01); A61K 31/7088 (2006.01); A61K 31/7105 (2006.01); A61K 31/711 (2006.01); A61K 47/54 (2017.01); A61P 27/02 (2006.01);
U.S. Cl.
CPC ...
C12N 15/115 (2013.01); A61K 9/0048 (2013.01); A61K 31/7088 (2013.01); A61K 31/711 (2013.01); A61K 31/7105 (2013.01); A61K 45/06 (2013.01); A61K 47/549 (2017.08); A61P 27/02 (2018.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01); C12N 2310/16 (2013.01); C12N 2310/317 (2013.01); C12N 2310/351 (2013.01); C12N 2310/3519 (2013.01); C12N 2320/51 (2013.01);
Abstract
Provided herein are compositions and methods for the treatment of retinal diseases. The compositions and methods include a therapeutic agent conjugated to a vitreous component binding moiety. The vitreous component binding moiety may be an aptamer or a small molecule that binds to a structural component of the vitreous humor (e.g., hyaluronic acid, collagen or vitronectin).