The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 04, 2019
Filed:
Mar. 06, 2014
Applicant:
Brandeis University, Waltham, MA (US);
Assignee:
Brandeis University, Waltham, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 5/072 (2006.01); A61K 38/00 (2006.01); A61P 35/00 (2006.01); A61K 31/195 (2006.01);
U.S. Cl.
CPC ...
C07K 5/06121 (2013.01); A61K 31/195 (2013.01);
Abstract
Disclosed herein are fibrillar molecular aggregates, which are morphologically and phenotypically similar to oligomers of aberrant proteins. The molecular aggregates, formed by self-assembly of small hydrophobic molecules, prevent the growth of microtubules. This unprecedented mechanism of 'self-assembly to interfere with self-organization' allows inhibition of the growth of cancer cells.