The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 04, 2019
Filed:
Oct. 18, 2016
Applicant:
Sunshine Lake Pharma Co., Ltd., Dongguan, Guangdong, CN;
Inventors:
Assignee:
SUNSHINE LAKE PHARMA CO., LTD., Dongguan, Guangdong, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 491/056 (2006.01); A61K 31/517 (2006.01); A61K 45/06 (2006.01); A61K 31/337 (2006.01); A61K 31/427 (2006.01); A61K 31/436 (2006.01); A61K 31/5355 (2006.01); A61K 31/573 (2006.01); A61K 31/7072 (2006.01); A61K 35/04 (2006.01); A61P 35/04 (2006.01);
U.S. Cl.
CPC ...
C07D 491/056 (2013.01); A61K 31/517 (2013.01); A61K 45/06 (2013.01); A61P 35/04 (2018.01); A61K 31/337 (2013.01); A61K 31/427 (2013.01); A61K 31/436 (2013.01); A61K 31/5355 (2013.01); A61K 31/573 (2013.01); A61K 31/7072 (2013.01); A61K 2300/00 (2013.01);
Abstract
The invention relates to a salt, a hydrate or a crystalline form of an EGFR inhibitor, and use thereof. Specifically it relates to 4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-[3-[(1R,6S)-2,5-dioxa-8-azabicyclo [4.3.0] nonan-8-yl] propoxy] quinazoline dimethanesulfonate, hydrate and a crystalline form thereof; the invention also relates to a preparation method of the crystalline form disclosed herein, a pharmaceutical composition containing the crystalline form, and uses thereof for treating proliferative disorders.