The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 04, 2019
Filed:
Mar. 17, 2016
Bristol-myers Squibb Company, Princeton, NJ (US);
Stephen T. Wrobleski, Flemington, NJ (US);
Gregory D. Brown, Lansdale, PA (US);
Shuqun Lin, Newtown, NJ (US);
Jingwu Duan, Yardley, PA (US);
Zhonghui Lu, King of Prussia, PA (US);
Murali T. G. Dhar, Newtown, PA (US);
Hai-Yun Xiao, Belle Mead, NJ (US);
Andrew J. Tebben, New Hope, PA (US);
Bristol-Myers Squibb Company, Princeton, NJ (US);
Abstract
Disclosed are compounds of Formula (I) or a salt thereof, wherein: X is N; W is: —(CR3R3)2-5-, —(CR3R3)x-Y—(CR3R3)y-, —Y—(CR3R3)2-3-Y—, —CR3R3-Y—(CR3R3)2-Y—, —Y—(CR3R3)2-Y—CR3R3-; and Y, R1, R2, R3, R5, R6, R8, x, and y are define herein. Also disclosed are methods of using such compounds as modulators of TNFα, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating inflammatory and autoimmune diseases.