The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 04, 2019
Filed:
Feb. 14, 2017
Bial—portela & CA S.a., S. Mamede do Coronado, PT;
Patricio Manuel Vieira Araújo Soares Da Silva, S. Mamede do Coronado, PT;
Maria João Macedo Da Silva Bonifácio, S. Mamede do Coronado, PT;
Bial-Portela & CA, S.A., S. Mamede do Coronado, PT;
Abstract
The present invention relates to compounds of formula I: for use in treating pulmonary arterial hypertension and associated conditions, where R, Rand Rare the same or different and signify hydrogens, halogens, alkyl, alkylaryl, alkyloxy, hydroxy, nitro, amino, alkylcarbonylamino, alkylamino or dialkylamino group; Rsignifies hydrogen, alkyl, -alkylaryl or -alkylheteroaryl; X signifies CH, oxygen atom or sulphur atom; n is 1, 2 or 3, with the proviso that when n is 1, X is not CH; and the individual (R)- and (S)-enantiomers or mixtures of enantiomers and pharmaceutically acceptable salts thereof.