The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 04, 2019
Filed:
Sep. 26, 2016
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Qinghao Chen, Edison, NJ (US);
Shane W. Krska, New Providence, NJ (US);
Lushi Tan, Edison, NJ (US);
Peter E. Maligres, Fanwood, NJ (US);
Jeremy Scott, Hertfordshire, GB;
Carl Baxter, Hertfordshire, GB;
Gavin William Stewart, Hertfordshire, GB;
Andrew Gibb, Hertfordshire, GB;
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Merck Sharp & Dohme Limited, Hoddesdon, Hertfordshire, unknown;
Abstract
This invention provides novel processes for the preparation of compounds such as 3-[(1S,2S)-2-hydroxycyclohexyl]-6-[(6-methylpyridin-3-yl)methyl]benzo[h]-quinazolin-4(3H)-one, salts and derivatives thereof. The compounds synthesized by the processes of the invention are useful for treating Alzheimer's disease and other diseases (e.g., cognitive impairment, schizophrenia, pain disorders, and sleep disorders) mediated by the muscarinic M1 receptor.