The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 04, 2019

Filed:

Mar. 18, 2016
Applicant:

Aurobindo Pharma Ltd, Telangana, Hyderabad, IN;

Inventors:

Sukumar Nandi, Hyderabad, IN;

Akkina Naresh, Hyderabad, IN;

Syam Prasad Reddy Rao Annareddy, Hyderabad, IN;

Gona Bala Narsimha Reddy, Hyderabad, IN;

Meenakshi Sunderam Sivakumaran, Hyderabad, IN;

Assignee:

Aurobindo Pharma Ltd, Hyderabad, IN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 223/16 (2006.01);
U.S. Cl.
CPC ...
C07D 223/16 (2013.01); C07B 2200/13 (2013.01);
Abstract

The present invention provides a process for the preparation of crystalline Lorcaserin hydrochloride hemihydrate of Formula (Ia), which comprises, Formula (Ia) (i) providing a solution of Lorcaserin base in a solvent; (ii) if water is present, removing water from the reaction mixture; (iii) adding hydrogen chloride to the reaction mixture; (iv) combining the reaction mixture with a suitable anti-solvent; and (v) isolating the crystalline Lorcaserin hydrochloride hemihydrate of Formula (Ia).


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