The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 04, 2019

Filed:

Jan. 30, 2015
Applicants:

The General Hospital Corporation, Boston, MA (US);

Massachusetts Institute of Technology, Cambridge, MA (US);

Inventors:

Mehmet Toner, Charlestown, MA (US);

Gareth McKinley, Acton, MA (US);

Eugene Lim, Charlestown, MA (US);

Thomas Ober, Cambridge, MA (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01L 99/00 (2010.01); B01L 3/00 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502776 (2013.01); B01L 3/50273 (2013.01); B01L 3/502715 (2013.01); B01L 2200/0636 (2013.01); B01L 2200/12 (2013.01); B01L 2400/0487 (2013.01);
Abstract

One example of systems and methods for inertio-elastic focusing of particles in microchannels includes a substrate including a channel having an inlet and an outlet. A viscoelastic fluid, i.e., a fluid having a dynamic viscosity that varies with shear rate, and that carries suspended particles is driven through the channel. The volumetric flow rate at which the fluid is driven results in the formation of a localized pathline in the fluid at or near a center of the channel. The localized pathline defines a width that is equal to or slightly greater than a hydraulic diameter of the particle. The particles in the fluid are focused into the localized pathline.


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