The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 04, 2019

Filed:

Jul. 11, 2014
Applicant:

Universite Francois Rabelais, Tours, FR;

Inventors:

Nicolas Joubert, Saint Avertin, FR;

Marie Claude Viaud-Massuard, Tours, FR;

Renaud Respaud, Tours, FR;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 51/00 (2006.01); A61M 36/14 (2006.01); A61K 47/48 (2006.01); C07D 207/456 (2006.01); C07K 16/32 (2006.01); A61K 49/00 (2006.01); A61K 51/02 (2006.01); C07K 16/28 (2006.01); C07K 16/40 (2006.01); C12N 9/10 (2006.01); C12N 9/24 (2006.01); A61K 47/65 (2017.01); A61K 47/68 (2017.01);
U.S. Cl.
CPC ...
A61K 47/48646 (2013.01); A61K 47/65 (2017.08); A61K 47/6849 (2017.08); A61K 47/6871 (2017.08); A61K 47/6889 (2017.08); A61K 49/00 (2013.01); A61K 51/02 (2013.01); C07D 207/456 (2013.01); C07K 16/2887 (2013.01); C07K 16/32 (2013.01); C07K 16/40 (2013.01); C12N 9/1077 (2013.01); C12N 9/24 (2013.01); C12N 9/2497 (2013.01); C12Y 204/02036 (2013.01); C12Y 302/00 (2013.01); C12Y 302/02022 (2013.01);
Abstract

Disclosed are novel antibody-drug conjugates and use thereof in therapy, in particular in anticancer or anti-inflammatory therapy, as well as synthetic products useful as linkers, composed of a linker head and a linker body, and also a method for preparing the linkers and the antibody-drug conjugates.


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