The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 04, 2019
Filed:
Jul. 27, 2016
Applicant:
National Taiwan Normal University, Taipei, TW;
Inventors:
Hsiu-Mei Hsieh, Taipei, TW;
Yi-Ren Wang, Taipei, TW;
Si-Tse Jiang, Taipei, TW;
Wen-Yih Jeng, Taipei, TW;
Yuan-Yow Chiou, Tainan, TW;
Assignee:
NATIONAL TAIWAN NORMAL UNIVERSITY, Taipei, TW;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/17 (2006.01); C07K 14/47 (2006.01); A61K 38/16 (2006.01); A01K 67/027 (2006.01);
U.S. Cl.
CPC ...
A61K 38/1709 (2013.01); A61K 38/16 (2013.01); C07K 14/47 (2013.01); A01K 67/0275 (2013.01); A01K 67/0276 (2013.01); A01K 2217/075 (2013.01); A01K 2227/105 (2013.01); A01K 2267/0306 (2013.01);
Abstract
Disclosed is a method of treating or preventing polycystic kidney disease (PKD) by administration of neutrophil geleatinase-associated lipocalin (Ngal) protein. Also, a transgenic non-human animal model is established to investigate the effect of overexpression of exogenous Ngal on PKD progression.