The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 04, 2019

Filed:

May. 27, 2015
Applicant:

Soonchunhyang University Industry Academy Cooperation Foundation, Chungcheongnam-do, KR;

Inventor:

Keon-Hyoung Song, Chungcheongnam-do, KR;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/08 (2019.01); A61K 9/00 (2006.01); C07K 7/06 (2006.01);
U.S. Cl.
CPC ...
A61K 38/08 (2013.01); A61K 9/0043 (2013.01); C07K 7/06 (2013.01);
Abstract

As described herein, an peptide of SEQ ID NO: 1 is modified at the terminal end. Specifically, the carboxyl-group of the leucine at the terminal end of the amino acid sequence FCIGRL (SEQ ID NO: 1) is modified with a —CONH. This modified peptide is used as a permeation enhancer to boost the mucous membrane permeation, thereby noticeably increasing the bioavailability of a drug that is administered together with the modified peptide. The drug to be administered with the modified peptide can be cyclosporine A.


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