The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 04, 2019

Filed:

Mar. 14, 2014
Applicant:

Astellas Institute for Regenerative Medicine, Marlborough, MA (US);

Inventors:

Robert P. Lanza, Clinton, MA (US);

Shi-Jiang Lu, Shrewsbury, MA (US);

Wei Wang, Rochester, MN (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/30 (2015.01); C12N 5/079 (2010.01); C12N 5/0797 (2010.01); A61K 35/545 (2015.01); C12N 5/0793 (2010.01); C12N 5/0735 (2010.01); C12N 5/074 (2010.01);
U.S. Cl.
CPC ...
A61K 35/545 (2013.01); A61K 35/30 (2013.01); C12N 5/062 (2013.01); C12N 5/0606 (2013.01); C12N 5/0623 (2013.01); C12N 5/0696 (2013.01); C12N 2500/33 (2013.01); C12N 2501/105 (2013.01); C12N 2501/13 (2013.01); C12N 2501/155 (2013.01); C12N 2501/235 (2013.01); C12N 2501/33 (2013.01); C12N 2501/385 (2013.01); C12N 2506/02 (2013.01);
Abstract

Methods are provided for the production of photoreceptor cells and photoreceptor progenitor cells from pluripotent stem cells. Additionally provided are compositions of photoreceptor cells and photoreceptor cells, as well as methods for the therapeutic use thereof. Exemplary methods may produce substantially pure cultures of photoreceptor cells and/or photoreceptor cells.


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