The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 04, 2019
Filed:
Apr. 04, 2018
Applicant:
University of Seoul Industry Cooperation Foundation, Seoul, KR;
Inventors:
Ha Won Kim, Seoul, KR;
Dong Hee Lee, Seongnam-si, KR;
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/045 (2006.01); A61K 31/015 (2006.01); A61P 17/06 (2006.01); A61P 17/04 (2006.01); A61P 37/00 (2006.01); A61K 31/075 (2006.01); A61K 31/12 (2006.01); A61K 31/215 (2006.01); A61K 31/336 (2006.01);
U.S. Cl.
CPC ...
A61K 31/045 (2013.01); A61K 31/015 (2013.01); A61K 31/075 (2013.01); A61K 31/12 (2013.01); A61K 31/215 (2013.01); A61K 31/336 (2013.01); A61P 17/04 (2018.01); A61P 17/06 (2018.01); A61P 37/00 (2018.01);
Abstract
The present invention relates to a pharmaceutical composition for preventing or treating autoimmune diseases having cedrol or a pharmaceutically acceptable salt thereof as an active ingredient. Particularly, the cedrol or the derivative thereof of the present invention inhibits the expression of IL-17A, and in particular, cedrol, cedryl acetate, and cedrene exhibit the effect of delaying the outbreak of psoriasis and treating thereof in a psoriasis animal model. Therefore, these compounds can be used for the treatment of autoimmune diseases mediated by IL-17.