The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 04, 2019
Filed:
Apr. 16, 2015
Jeju National University Industry—academic Cooperation Foundation, Jeju-si, Jeju-do, KR;
Se Pill Park, Seoul, KR;
Young Sok Choi, Seoul, KR;
Eun Young Kim, Seoul, KR;
Young Ho Kim, Gyeonggi-do, KR;
Hyun Seok Hong, Gyeonggi-do, KR;
Chan Kyu Park, Seoul, KR;
Mi Seon Park, Seoul, KR;
Jeju National University Industry-Academic Cooperation Foundation, Jeju-si, Jeju-do, KR;
Abstract
The present invention relates to expression cassettes and vectors comprising Alzheimer's disease-related genes and a cell line transformed by the disclosed expression cassettes and vectors, and more specifically, the expression cassettes according to the present invention comprise amyloid precursor protein (APP), Tau protein, and presenilin-1 (PS1) genes associated with Alzheimer's disease so that mutant genes thereof can be simultaneously expressed. Additionally, the present invention relates to a cell line transformed by the disclosed expression cassettes or vectors comprising APP, Tau protein, and PS1 genes, and further, to an animal model transformed by the vectors or cell line.