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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10302662 B1

PDFFull Text
Date of Patent:
May. 28, 2019

Filed:

May. 16, 2016

Methods and kits for assessing heparanase procoagulant activity, compositions comprising heparanase, and methods for the treatment of coagulation related disorders

Applicant:

Rambam Med-tech, Haifa, IL;

Inventors:

Yona Nadir, Zichron Yaakovv, IL;

Benjamin Brenner, Haifa, IL;

Israel Vlodavsky, Haifa, IL;

Assignee:

RAMBAM MED-TECH, Haifa, IL;

Attorneys:

The Roy Gross Law Firm

Roy Gross

Primary Examiner:

Renee Claytor

Assistant Examiner:

Sharon M Papciak

Int. Cl.
CPC ...
A61K 38/36 (2006.01); A61K 38/47 (2006.01); A61K 38/55 (2006.01); A61K 31/5377 (2006.01); A61K 31/727 (2006.01); A61K 38/08 (2006.01); A61K 38/10 (2006.01); A61K 38/51 (2006.01); A61K 45/06 (2006.01); G01N 33/86 (2006.01); C07K 14/81 (2006.01); C07K 14/745 (2006.01);
U.S. Cl.
CPC ...
G01N 33/86 (2013.01); A61K 31/5377 (2013.01); A61K 31/727 (2013.01); A61K 38/08 (2013.01); A61K 38/10 (2013.01); A61K 38/36 (2013.01); A61K 38/47 (2013.01); A61K 38/51 (2013.01); A61K 38/55 (2013.01); A61K 45/06 (2013.01); C07K 14/745 (2013.01); C07K 14/8114 (2013.01); C12Y 302/01166 (2013.01); G01N 2333/924 (2013.01);
Abstract

Methods and kits for determining heparanase procoagulant activity in a biological sample are provided. Diagnostic methods for the detection and/or monitoring of a coagulation-related pathological disorder in a mammalian subject are further provided. In addition, compositions comprising heparanase and at least one tissue factor, uses and methods based thereon in the treatment, amelioration and prevention of coagulation-related pathologic conditions are provided. Also provided are methods for screening a coagulation modulatory compound, methods and uses based thereon in the treatment, amelioration and prevention of coagulation-related pathologic conditions.

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Nadir, Yona. (2019). Methods and kits for assessing heparanase procoagulant activity, compositions comprising heparanase, and methods for the treatment of coagulation related disorders (U.S. Patent No. 10302662). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10302662

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