The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 28, 2019

Filed:

Jun. 14, 2018
Applicant:

The Trustees of Columbia University IN the City of New York, New York, NY (US);

Inventors:

Yao Zong Ng, Singapore, SG;

Pedro Alexis Baldera Aguayo, New York, NY (US);

Virginia W. Cornish, New York, NY (US);

Ehud Herbst, New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/58 (2006.01); G01N 21/64 (2006.01); C12N 15/10 (2006.01); G01N 33/569 (2006.01); C40B 40/02 (2006.01); C12Q 1/68 (2018.01); G01N 33/542 (2006.01);
U.S. Cl.
CPC ...
G01N 33/582 (2013.01); C12N 15/10 (2013.01); C12N 15/1086 (2013.01); C12Q 1/68 (2013.01); C40B 40/02 (2013.01); G01N 21/64 (2013.01); G01N 33/542 (2013.01); G01N 33/569 (2013.01); G01N 33/56944 (2013.01);
Abstract

The present disclosure provides a high-throughput fluorescence polarization microorganism screening assay for a metabolite produced by a microorganism. The metabolite is detected using competition with a fluorescent reporter for a receptor that binds both the metabolite and the reporter. The present disclosure further provides materials used in such an assay, a kit for such an assay, an isolated microorganism identified using such an assay, and culture conditions identified using such an assay.


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