The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 28, 2019
Filed:
Oct. 20, 2015
Applicant:
Dana-farber Cancer Institute, Inc., Boston, MA (US);
Inventors:
Teru Hideshima, Brookline, MA (US);
Kenneth C. Anderson, Wellesley, MA (US);
Francesca Cottini, Boston, MA (US);
Assignee:
Dana-Farber Cancer Institute, Inc., Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); C12N 15/11 (2006.01); G01N 33/574 (2006.01); C12Q 1/48 (2006.01); G01N 33/573 (2006.01);
U.S. Cl.
CPC ...
G01N 33/57426 (2013.01); C12Q 1/485 (2013.01); G01N 33/573 (2013.01); G01N 2333/912 (2013.01);
Abstract
The invention provides, inter alia, methods of prognosing the survival of a multiple myeloma patient based levels of TP53RK in multiple myeloma cells of the patient. Also provided are methods of screening for therapeutic agents for treating multiple myeloma based on their ability to decrease TP53RK levels or activity in a patient with multiple myeloma.