The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 28, 2019

Filed:

Jan. 30, 2018
Applicant:

General Electric Company, Schenectady, NY (US);

Inventors:

Paul Charles Melanson, Boulder, CO (US);

Vidyasankar Sundaresan, Trevose, PA (US);

Richard Douglas Godec, Boulder, CO (US);

Shouquan Deng, Shanghai, CN;

Assignee:

GENERAL ELECTRIC COMPANY, Schenectady, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/569 (2006.01); B01L 3/00 (2006.01); G01N 33/579 (2006.01); G01N 21/17 (2006.01);
U.S. Cl.
CPC ...
G01N 33/56911 (2013.01); B01L 3/5027 (2013.01); B01L 3/5085 (2013.01); B01L 3/502715 (2013.01); G01N 21/17 (2013.01); G01N 33/579 (2013.01); B01L 2200/0605 (2013.01); B01L 2200/0684 (2013.01); B01L 2300/021 (2013.01); B01L 2300/087 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0829 (2013.01); B01L 2300/0861 (2013.01); B01L 2300/0864 (2013.01); B01L 2300/0867 (2013.01); B01L 2300/16 (2013.01); B01L 2400/0406 (2013.01); B01L 2400/0409 (2013.01); B01L 2400/049 (2013.01); B01L 2400/0487 (2013.01); B01L 2400/0622 (2013.01); B01L 2400/0688 (2013.01); B01L 2400/0694 (2013.01); G01N 2400/10 (2013.01); G01N 2400/50 (2013.01); Y10T 436/2575 (2015.01);
Abstract

Methods and systems for measuring the concentration of LAL-reactive substances in fluid samples is provided. They include contacting an aqueous sample with a detection reagent to form a prepared sample. A physical property of the prepared sample may be measured to obtain at least one sample measurement characteristic of the prepared sample. Curve fitting may then be used to forecast a concentration of the LAL-reactive substance the aqueous sample will have at a specified time in the future based on the sample measurement and a correlation developed between at least one standard measurement of a physical quality of a solution with a known concentration of a LAL-reactive substance therein. The quality of the sample measurement may be validated using historical data and/or the standard measurement.


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