The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 28, 2019

Filed:

Mar. 29, 2016
Applicant:

France Carrier, Highland, MD (US);

Inventor:

France Carrier, Highland, MD (US);

Assignee:

UNIVERSITY OF MARYLAND, BALTIMORE, Baltimore, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); G01N 33/50 (2006.01); C07K 16/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5011 (2013.01); C07K 16/00 (2013.01); C12N 15/113 (2013.01); C12N 2310/14 (2013.01);
Abstract

The present invention is drawn to therapeutics which can target hnRNP A18, a regulator of protein translation in cancer cells. The invention provides a method of treating cancer in a subject comprising administering to the subject a therapeutically effective amount of a composition that decreases the level and/or activity of heterogenous ribonucleoprotein A18 (hnRNP A18). The composition can comprise a nucleic acid molecule that binds to at least a portion of a nucleotide sequence coding for hnRNP A18. The invention also provides a composition for treating cancer comprising a nucleic acid or antibody that is capable of decreasing the level and/or activity of hnRNP A18 and a pharmaceutically acceptable carrier. The invention also provides methods of screening for an anti-cancer compound.


Find Patent Forward Citations

Carrier, France. (2019). Compositions and methods for treating cancer by rational targeting of protein translation (U.S. Patent No. 10302629). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10302629

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