The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 28, 2019

Filed:

Jan. 15, 2016
Applicant:

Centre for Addiction and Mental Health, Toronto, Ontario, CA;

Inventor:

Jeff Meyer, Toronto, CA;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); G01N 33/49 (2006.01); G01N 33/48 (2006.01); G01N 33/88 (2006.01);
U.S. Cl.
CPC ...
G01N 33/49 (2013.01); G01N 33/48 (2013.01); G01N 33/88 (2013.01); G01N 2333/4737 (2013.01); G01N 2800/304 (2013.01);
Abstract

Provided are methods for determining the level of microglial activation in the brain of a subject by measuring blood Prostaglandin E2 (PGE2), Prostaglandin F2α, or both, and C-Reactive Protein (CRP) concentrations in a sample obtained from a subject, wherein the ratio of [PGE2]/[CRP], [PGF2α]/[CRP], or both, is indicative of the level of microglial activation in the brain of the subject.


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