The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 28, 2019

Filed:

Mar. 24, 2016
Applicants:

The University of Tokyo, Bunkyo-ku, Tokyo, JP;

Nikon Corporation, Chiyoda-ku, Tokyo, JP;

Inventors:

Takanori Ichiki, Tokyo, JP;

Masashi Kobayashi, Tokyo, JP;

Ayako Hayashi, Kuki, JP;

Shoichi Tsuchiya, Chigasaki, JP;

Takanori Akagi, Tokyo, JP;

Taro Ueno, Tokyo, JP;

Takashi Funatsu, Tokyo, JP;

Kenji Miyamoto, Yokohama, JP;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6886 (2018.01); G01N 33/53 (2006.01); B01L 3/00 (2006.01); C12Q 1/6806 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); B01L 3/5027 (2013.01); B01L 3/502715 (2013.01); B01L 3/502761 (2013.01); C12Q 1/6806 (2013.01); G01N 33/5308 (2013.01); B01L 2200/0631 (2013.01); B01L 2200/10 (2013.01); B01L 2300/0627 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0861 (2013.01); B01L 2300/0864 (2013.01); B01L 2300/0867 (2013.01); B01L 2300/161 (2013.01); B01L 2300/165 (2013.01); B01L 2400/0487 (2013.01); C12Q 2600/158 (2013.01); C12Q 2600/16 (2013.01); C12Q 2600/178 (2013.01);
Abstract

The present invention provides a fluidic device, an exosome analysis method, a biomolecule analysis method, and a biomolecule detection method, which can analyze even the content of an exosome in a series of flows by introducing a sample into the device. A fluidic device of the present invention is a fluidic device which detects a biomolecule contained in an exosome in a sample, and includes: an exosome purification unit which has a layer modified with a compound having a hydrophobic chain and a hydrophilic chain; a biomolecule purification unit; a biomolecule detection unit; a first flow path which connects the exosome purification unit to the biomolecule purification unit; and a second flow path which connects the biomolecule purification unit to the biomolecule detection unit.


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