The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 28, 2019

Filed:

May. 23, 2017
Applicant:

Cellular Research, Inc., Menlo Park, CA (US);

Inventors:

Eleen Shum, Menlo Park, CA (US);

Glenn Fu, Menlo Park, CA (US);

Craig Betts, Menlo Park, CA (US);

Assignee:

Cellular Research, Inc., San Jose, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); C12Q 1/6874 (2018.01); C12Q 1/6806 (2018.01); G06F 19/20 (2011.01); C12N 15/10 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6874 (2013.01); C12N 15/1065 (2013.01); C12N 15/1093 (2013.01); C12Q 1/6806 (2013.01); G06F 19/20 (2013.01);
Abstract

This disclosure provides methods and compositions for removing one or more high abundance species from a plurality of nucleic acid molecules. In some embodiments, the methods and compositions can be used for normalizing nucleic acid libraries. In some embodiments, molecular labels are used in conjunction with the methods and compositions disclosed herein to improve sequencing efficiency.


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