The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 28, 2019

Filed:

Aug. 15, 2017
Applicant:

Chromacode, Inc., Carlsbad, CA (US);

Inventors:

Lucien A. E. Jacky, Orange, CA (US);

Aditya Rajagopal, Orange, CA (US);

Karen L. Menge, San Marcos, CA (US);

Gregory Gosch, San Diego, CA (US);

Assignee:

CHROMACODE, INC., Carlsbad, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 19/34 (2006.01); C12Q 1/6818 (2018.01); C12Q 1/6804 (2018.01); C12Q 1/6827 (2018.01); C12Q 1/6888 (2018.01); G01N 21/64 (2006.01); G01N 33/58 (2006.01); C12Q 1/6816 (2018.01); C12Q 1/686 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6818 (2013.01); C12Q 1/6804 (2013.01); C12Q 1/686 (2013.01); C12Q 1/6816 (2013.01); C12Q 1/6827 (2013.01); C12Q 1/6888 (2013.01); G01N 21/6428 (2013.01); G01N 33/58 (2013.01); C12Q 2537/143 (2013.01);
Abstract

A method of identifying a first target nucleic acid comprising, providing a sample comprising the first target nucleic acid, providing a first set of paired oligonucleotides with complementarity to the first target nucleic acid, the first set of paired oligonucleotides comprising a first ratio of (a) first competitive oligonucleotides to (b) first signal oligonucleotides comprising a signal tag, wherein the competitive oligonucleotides compete with the signal oligonucleotides for binding to the first target nucleic acid, amplifying the first target nucleic acid with the polymerase chain reaction, thereby degrading the first signal oligonucleotide and permitting generation of a first signal, generating the first signal, measuring intensity of the first signal, and correlating the intensity of the first signal to the first ratio, thereby identifying the first target nucleic acid.


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