The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 28, 2019
Filed:
Feb. 01, 2016
Applicant:
Wyeth Llc, New York, NY (US);
Inventors:
Wei-Qiang Willie Sun, Morristown, NJ (US);
Earl Joseph Pursell, Valley Cottage, NY (US);
Assignee:
Wyeth, LLC, New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C12P 21/00 (2006.01); C07K 14/22 (2006.01); C12P 21/02 (2006.01);
U.S. Cl.
CPC ...
C12P 21/00 (2013.01); C07K 14/22 (2013.01); C12P 21/02 (2013.01);
Abstract
Methods for producing proteins, for example, recombinant meningococcal 2086 proteins, using fed-batch fermentation with continuous input of an inducer after achieving a threshold parameter, and continuous input of a carbon source, for example, a constant rate input, to improve protein yields, as well as high density protein compositions for use in the methods of the present invention, are provided.