The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 28, 2019
Filed:
Apr. 15, 2015
Applicant:
Griffith University, Nathan, Queensland, AU;
Inventors:
Assignee:
Griffith University, Nathan, Queensland, AU;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/315 (2006.01); C07K 16/12 (2006.01); A61K 39/09 (2006.01); A61K 38/48 (2006.01); A61K 39/395 (2006.01); C07K 16/40 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/315 (2013.01); A61K 38/4873 (2013.01); A61K 39/092 (2013.01); A61K 39/3955 (2013.01); C07K 16/1275 (2013.01); C07K 16/40 (2013.01); C12Y 304/22 (2013.01); A61K 2039/505 (2013.01); C07K 2317/34 (2013.01); C07K 2317/76 (2013.01);
Abstract
A method and composition for eliciting an immune response to group A streptococcal bacteria in a mammal is provided, which includes administering to the mammal an M protein fragment, variant or derivative thereof and a SpyCEP protein or peptide fragment, or an antibody to the SpyCEP protein or fragment to facilitate restoring or enhancing neutrophil activity. Also provided is an immunodominant peptide fragment of SpyCEP.