The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 28, 2019
Filed:
Jun. 27, 2018
Applicant:
Novartis Ag, Basel, CH;
Inventors:
Sangamesh Badiger, Bangalore, IN;
Murali Chebrolu, Andhra Pradesh, IN;
Konstanze Hurth, Lorrach, DE;
Sebastien Jacquier, Hegenheim, FR;
Rainer Martin Lueoend, Therwill, CH;
Rainer Machauer, Freiburg, DE;
Heinrich Rueeger, Flueh, CH;
Marina Tintelnot-Blomley, Maulburg, DE;
Siem Jacob Veenstra, Lorrach, DE;
Markus Voegtle, Lorrach, DE;
Assignee:
Novartis AG, Basel, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/14 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01); A61K 31/5377 (2006.01); C07B 59/00 (2006.01);
U.S. Cl.
CPC ...
C07D 413/14 (2013.01); A61K 31/5377 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07B 59/002 (2013.01); C07B 2200/05 (2013.01);
Abstract
The invention relates to novel heterocyclic compounds of the formula in which all of the variables are as defined in the specification, pharmaceutical compositions thereof, combinations thereof, and their use as medicaments, particularly for the treatment of Alzheimer's Disease or diabetes via inhibition of BACE-1 or BACE-2.