The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 28, 2019
Filed:
Dec. 04, 2017
Applicant:
Topivert Pharma Limited, London, GB;
Inventor:
Matthew Colin Thor Fyfe, London, GB;
Assignee:
Topivert Pharma Limited, London, GB;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 213/63 (2006.01); C07D 403/12 (2006.01); A61K 31/5377 (2006.01); C07D 401/14 (2006.01); C07D 401/12 (2006.01); A61K 31/4439 (2006.01); A61K 31/506 (2006.01); A61K 31/675 (2006.01); A61K 45/06 (2006.01); C07F 9/46 (2006.01);
U.S. Cl.
CPC ...
C07D 403/12 (2013.01); A61K 31/4439 (2013.01); A61K 31/506 (2013.01); A61K 31/5377 (2013.01); A61K 31/675 (2013.01); A61K 45/06 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07F 9/46 (2013.01);
Abstract
There are provided compounds of formula (III), or a salt or protected derivative thereof, wherein Zrepresents a structural fragment of formula (V), wherein R, R, R, X and Y have meanings given in the description, which compounds have antiinflammatory activity, for example through inhibition of one or more of members of: the family of p38 mitogen-activated protein kinase enzymes; Syk kinase; and members of the Src family of tyrosine kinases) and have use in therapy, including in pharmaceutical combinations, especially in the treatment of inflammatory diseases, including inflammatory diseases of the lung, eye and intestines.