The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 28, 2019

Filed:

Sep. 14, 2016
Applicants:

Zhejiang Jingxin Pharmaceutical Co., Ltd., Zhejiang, CN;

Shanghai Jingxin Biomedical Co., Ltd., Pudong Shanghai, CN;

Shangyu Jingxin Pharmaceutical Co., Ltd., Shangyu, Zhejiang, CN;

Inventors:

Yue Huang, Shanghai, CN;

Fei Zheng, Shanghai, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 275/26 (2006.01); C07D 333/54 (2006.01); C07D 333/72 (2006.01); C07D 413/04 (2006.01); A61P 25/18 (2006.01); A61K 9/20 (2006.01); A61K 31/454 (2006.01); A61K 31/496 (2006.01); C07D 261/20 (2006.01); C07D 409/04 (2006.01); C07D 417/04 (2006.01); C07D 275/04 (2006.01);
U.S. Cl.
CPC ...
C07D 333/54 (2013.01); A61K 9/2013 (2013.01); A61K 9/2018 (2013.01); A61K 9/2054 (2013.01); A61K 9/2059 (2013.01); A61K 31/454 (2013.01); A61K 31/496 (2013.01); A61P 25/18 (2018.01); C07D 261/20 (2013.01); C07D 275/04 (2013.01); C07D 333/72 (2013.01); C07D 409/04 (2013.01); C07D 413/04 (2013.01); C07D 417/04 (2013.01);
Abstract

A cyclohexane derivative as shown by formula IB or a stereoisomer or a salt thereof, has a high affinity for Dreceptors and 5-hydroxytryptamine, has a lower affinity for Dreceptors, shows a high selectivity for D/Dreceptors, and can be used as a therapeutic drug against neuropsychiatric diseases. wherein; X is N or CH; R is R is optionally substituted with one or more substituents selected from the group consisting of F, Cl, Br, I and C-Calkyl; and the C-Calkyl is optionally substituted with one or more substituents selected from the group consisting of F, Cl, Br, and I.


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