The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 28, 2019
Filed:
May. 29, 2013
Applicant:
Phenex Pharmaceuticals Ag, Ludwigshafen, DE;
Inventors:
Christian Gege, Ehingen, DE;
Christoph Steeneck, Dossenheim, DE;
Olaf Kinzel, Heidelberg, DE;
Gerald Kleymann, Bad Salzuflen, DE;
Thomas Hoffmann, Viernheim, DE;
Assignee:
Phenex Pharmaceuticals AG, Ludwigshafen, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 333/38 (2006.01); C07D 493/10 (2006.01); C07D 405/12 (2006.01); C07D 413/12 (2006.01); C07D 417/04 (2006.01); C07D 417/06 (2006.01); C07D 417/12 (2006.01); C07D 417/14 (2006.01); C07D 453/02 (2006.01); C07D 263/34 (2006.01); C07D 487/08 (2006.01); C07D 491/10 (2006.01); C07D 495/10 (2006.01); C07D 277/36 (2006.01); C07D 498/08 (2006.01); C07D 277/46 (2006.01); C07D 277/52 (2006.01); C07D 277/56 (2006.01); C07D 307/08 (2006.01); C07D 455/02 (2006.01); C07D 493/08 (2006.01); C07D 239/28 (2006.01); C07D 307/68 (2006.01);
U.S. Cl.
CPC ...
C07D 277/56 (2013.01); C07D 239/28 (2013.01); C07D 263/34 (2013.01); C07D 277/36 (2013.01); C07D 277/46 (2013.01); C07D 277/52 (2013.01); C07D 307/68 (2013.01); C07D 333/38 (2013.01); C07D 405/12 (2013.01); C07D 413/12 (2013.01); C07D 417/04 (2013.01); C07D 417/06 (2013.01); C07D 417/12 (2013.01); C07D 417/14 (2013.01); C07D 453/02 (2013.01); C07D 455/02 (2013.01); C07D 487/08 (2013.01); C07D 491/10 (2013.01); C07D 493/08 (2013.01); C07D 493/10 (2013.01); C07D 495/10 (2013.01); C07D 498/08 (2013.01);
Abstract
The invention provides modulators for the orphan nuclear receptor RORy and methods for treating RORy mediated diseases by administering these novel RORy modulators to a human or a mammal in need thereof. Specifically, the present invention provides carboxamide or sulfonamide containing cyclic compounds of Formula (1), (1'), (100), (100′), (200) and (200′) and the enantiomers, diastereomers, tautomers, /V-oxides, solvates and pharmaceutically acceptable salts thereof.