The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 28, 2019

Filed:

Dec. 29, 2016
Applicant:

Washington University, St. Louis, MO (US);

Inventors:

Zhude Tu, Frontenac, MO (US);

Junfeng Li, Duarte, CA (US);

Xuyi Yue, St. Louis, MO (US);

Paul Kotzbauer, Clayton, MO (US);

Assignee:

Washington University, St. Louis, MO (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 51/04 (2006.01); C07B 59/00 (2006.01);
U.S. Cl.
CPC ...
A61K 51/0459 (2013.01); A61K 51/0455 (2013.01); A61K 51/0463 (2013.01); A61K 51/0465 (2013.01); C07B 59/002 (2013.01);
Abstract

The present invention generally relates to various compounds that are useful as α-synuclein ligands. The invention further relates to methods of using these compounds and their radiolabeled analogs for the detection of synucleinopathies, including Parkinson's disease (PD).


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