The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 28, 2019
Filed:
Oct. 11, 2017
Applicant:
University of Houston System, Houston, TX (US);
Inventors:
Assignee:
University of Houston System, Houston, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); A61K 31/7105 (2006.01); A61K 45/06 (2006.01); C12N 5/077 (2010.01); C12N 15/00 (2006.01); A61K 9/00 (2006.01); A61K 9/14 (2006.01); C12N 7/00 (2006.01); C12N 15/11 (2006.01);
U.S. Cl.
CPC ...
A61K 48/0058 (2013.01); A61K 9/0019 (2013.01); A61K 9/14 (2013.01); A61K 31/7105 (2013.01); A61K 45/06 (2013.01); A61K 48/00 (2013.01); A61K 48/0025 (2013.01); A61K 48/0075 (2013.01); A61K 48/0083 (2013.01); C12N 5/0657 (2013.01); C12N 7/00 (2013.01); C12N 15/00 (2013.01); C12N 15/111 (2013.01); C12N 2310/141 (2013.01); C12N 2320/30 (2013.01); C12N 2501/65 (2013.01); C12N 2506/02 (2013.01); C12N 2710/10043 (2013.01); C12N 2740/10043 (2013.01);
Abstract
The present disclosure describes the role for miR-322(424)/503 in the differentiation of cardiac precursor cells. Thus, the use of these molecules in the programming of resident stem/progenitor cells into cardiomyocytes, both in vitro and in vivo. Such methods find particular use in the treatment of patients post-myocardial infarction to prevent or limit scarring and to promote myocardial repair.