The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 28, 2019
Filed:
Jul. 29, 2016
Applicant:
The Trustees of Princeton University, Princeton, NJ (US);
Inventors:
Thomas Shenk, Princeton, NJ (US);
Dai Wang, Blue Bell, PA (US);
Assignee:
The Trustees of Princeton University, Princeton, NJ (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/11 (2006.01); A61K 39/245 (2006.01); A61K 39/12 (2006.01); C12N 7/00 (2006.01); A61K 39/145 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/245 (2013.01); A61K 39/12 (2013.01); C12N 7/00 (2013.01); A61K 2039/5252 (2013.01); A61K 2039/5254 (2013.01); A61K 2039/54 (2013.01); C12N 2710/16134 (2013.01); C12N 2710/16151 (2013.01); C12N 2710/16164 (2013.01);
Abstract
Methods of increasing diversity in cytomegalovirus vaccines through the selection of cell type in which the virus is propagated, and the use of cytomegalovirus produced by those methods in the development of vaccine compositions, are disclosed. Vaccine compositions comprising CMV isolated from epithelial cells are also disclosed.