The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 28, 2019
Filed:
Feb. 07, 2014
Applicant:
Midatech Limited, Abingdon, GB;
Inventors:
Thomas Rademacher, Oxfordshire, GB;
David K. Male, Milton Keynes, GB;
Assignee:
Midatech Ltd., Oxfordshire, GB;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/51 (2006.01); A61K 9/00 (2006.01); A61K 49/18 (2006.01); B82Y 5/00 (2011.01); A61K 38/17 (2006.01); A61K 39/395 (2006.01);
U.S. Cl.
CPC ...
A61K 9/5123 (2013.01); A61K 9/0009 (2013.01); A61K 9/5115 (2013.01); A61K 9/5192 (2013.01); A61K 38/1709 (2013.01); A61K 39/3955 (2013.01); A61K 49/1824 (2013.01); B82Y 5/00 (2013.01); Y10S 977/773 (2013.01); Y10S 977/788 (2013.01); Y10S 977/81 (2013.01); Y10S 977/906 (2013.01); Y10S 977/93 (2013.01);
Abstract
Nanoparticle delivery systems for use in targeting biologically active agents to the central nervous system comprise a composition comprising (a) a nanoparticle comprising: (i) a core comprising a metal and/or a semiconductor; and (ii) a corona comprising a plurality of ligands covalently linked to the core, wherein said ligands comprise a carbohydrate, insulin and/or a glutathione; and (b) the at least one agent to be delivered to the CNS. Methods of treatment and diagnosing CNS disorders utilizing the nanoparticle delivery systems and related screening methods are also disclosed.